Use of Furadantin and Macrodantin (Nitrofurantoin)

Do not give Furadantin and Macrodantin (Nitrofurantoin) to infants up to 1 month of age.

Furadantin and Macrodantin (Nitrofurantoin) is best taken with food or milk. This may lessen stomach upset and help your body to better absorb the medicine.

For patients taking the oral liquid form of Furadantin and Macrodantin (Nitrofurantoin) :

Shake the oral liquid forcefully before each dose to help make it pour more smoothly and to be sure the medicine is evenly mixed.

Use a specially marked measuring spoon or other device to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.

Furadantin and Macrodantin (Nitrofurantoin) may be mixed with water, milk, fruit juices, or infants' formulas. If it is mixed with any of these liquids, take the medicine immediately after mixing. Be sure to drink all the liquid in order to get the full dose of medicine.

For patients taking the extended-release capsule form of Furadantin and Macrodantin (Nitrofurantoin):

Swallow the capsules whole. Do not open, crush, or chew the capsules before swallowing them.
To help clear up your infection completely, keep taking Furadantin and Macrodantin (Nitrofurantoin) for the full time of treatment, even if you begin to feel better after a few days. Do not miss any doses.

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Dose of Furadantin and Macrodantin (Nitrofurantoin)

The dose of Furadantin and Macrodantin (Nitrofurantoin) will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of Furadantin and Macrodantin (Nitrofurantoin). If your dose is different, do not change it unless your doctor tells you to do so.

For the capsule, oral suspension, and tablet dosage forms of Furadantin and Macrodantin (Nitrofurantoin) :

For the prevention of urinary tract infection:

Adults and adolescents—50 to 100 mg once a day at bedtime.

Children 1 month of age and older—Dose is based on body weight and must be determined by your doctor.

Children up to 1 month of age—Use is not recommended.

For the treatment of urinary tract infection:

Adults and adolescents—50 to 100 mg every six hours.

Children 1 month of age and older—Dose is based on body weight and must be determined by your doctor.

Children up to 1 month of age—Use is not recommended.

For the extended-release capsule dosage form of Furadantin and Macrodantin (Nitrofurantoin) :

Adults and children 12 years of age and older: 100 mg every twelve hours for seven days.

Children up to 12 years of age: Dose must be determined by the doctor.

Missed Dose of Furadantin and Macrodantin (Nitrofurantoin)

If you miss a dose of Furadantin and Macrodantin (Nitrofurantoin) , apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage of Furadantin and Macrodantin (Nitrofurantoin)

• Keep Furadantin and Macrodantin (Nitrofurantoin) out of the reach of children.
• Store Furadantin and Macrodantin (Nitrofurantoin) away from heat and direct light.
• Do not store Furadantin and Macrodantin (Nitrofurantoin) in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause Furadantin and Macrodantin (Nitrofurantoin) to break down.
• Do not keep outdated Furadantin and Macrodantin (Nitrofurantoin) or Furadantin and Macrodantin (Nitrofurantoin) no longer needed.
• Be sure that any discarded medicine is out of the reach of children. Keep out of the reach of children.

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Precautions While Using Furadantin and Macrodantin (Nitrofurantoin)

It is important that your doctor check your progress at regular visits if you will be taking Furadantin and Macrodantin (Nitrofurantoin) for a long time.

If your symptoms do not improve within a few days, or if they become worse, check with your doctor.

For diabetic patients:

Furadantin and Macrodantin (Nitrofurantoin) may cause false test results with some urine sugar tests. Check with your doctor before changing your diet or the dosage of your diabetes medicine.

Side Effects of Furadantin and Macrodantin (Nitrofurantoin)

Along with its needed effects, Furadantin and Macrodantin (Nitrofurantoin) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common
Changes in facial skin color; chest pain; chills; cough; fever; general feeling of discomfort or illness; hives; hoarseness ; itching; joint or muscle pain; shortness of breath; skin rash; sudden trouble in swallowing or breathing ; swelling of face, mouth, hands, or feet; troubled breathing

Less common
Black, tarry stools; blood in urine or stools; burning, numbness, tingling, or painful sensations; dizziness; drowsiness; headache; pinpoint red spots on skin; sore throat; unusual bleeding or bruising; unusual tiredness or weakness; weakness in arms, hands, legs, or feet

Rare
Abdominal or stomach pain; blistering, peeling, or loosening of skin and mucous membranes; bluish color of skin; blurred vision or loss of vision, with or without eye pain; bulging fontanel in infants ; confusion; darkening of urine; diarrhea, watery and severe, which may also be bloody; loss of appetite; mental depression; mood or mental changes; nausea or vomiting; pale skin; pale stools; red skin lesions, often with a purple center; red, thickened, or scaly skin ; skin rash; sores, ulcers, or white spots on lips or in mouth; swollen or painful glands; unpleasant breath odor; visual changes; vomiting of blood; wheezing or tightness in chest; yellow eyes or skin

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

More common
Diarrhea; gas

After you stop using Furadantin and Macrodantin (Nitrofurantoin), your body may need time to adjust. The length of time this takes depends on the amount of medicine you were using and how long you used it. During this period of time check with your doctor immediately if you notice any of the following side effects:

Abdominal or stomach cramps or pain, severe; diarrhea, watery and severe, which may also be bloody; fever

Furadantin and Macrodantin (Nitrofurantoin) may cause the urine to become rust-yellow to brown. This side effect does not require medical attention.

Furadantin and Macrodantin (Nitrofurantoin) may cause a temporary loss of hair in some people.

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.

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