Use of Bactrim, (Trimethoprim 80mg/Sulfamethoxazole 400mg)

Bactrim / (Sulfamethoxazole and Trimethoprim) combination should not be given to infants less than 2 months of age unless directed by the child's doctor. These medicines may cause unwanted effects in the baby. In special situations, Bactrim / (Sulfamethoxazole and Trimethoprim) combination may be given to infants less than 2 months of age.

Bactrim / (Sulfamethoxazole and Trimethoprim) combinations are best taken with a full glass (8 ounces) of water. Several additional glasses of water should be taken every day, unless otherwise directed by your doctor. Drinking extra water will help to prevent some unwanted effects of sulfonamides.

For patients taking the oral liquid form of Bactrim / (Sulfamethoxazole and Trimethoprim):

Use a specially marked measuring spoon or other device to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.
To help clear up your infection completely, keep taking Bactrim / (Sulfamethoxazole and Trimethoprim) for the full time of treatment, even if you begin to feel better after a few days. If you stop taking Bactrim / (Sulfamethoxazole and Trimethoprim) too soon, your symptoms may return.

Bactrim / (Sulfamethoxazole and Trimethoprim) works best when there is a constant amount in the blood or urine. To help keep the amount constant, do not miss any doses. Also, it is best to take the doses at evenly spaced times day and night. If you need help in planning the best times to take your medicine, check with your health care professional.

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Dose of Bactrim, (Trimethoprim 80mg/Sulfamethoxazole 400mg)

The dose of Bactrim, (Trimethoprim 80mg/Sulfamethoxazole 400mg) will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of Bactrim, (Trimethoprim 80mg/Sulfamethoxazole 400mg) . If your dose of Bactrim, (Trimethoprim 80mg/Sulfamethoxazole 400mg) is different, do not change it unless your doctor tells you to do so.

The number of tablets or teaspoonfuls of suspension that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are taking Bactrim, (Trimethoprim 80mg/Sulfamethoxazole 400mg) .

For bacterial infections:

Adults and children 40 kilograms (kg) of body weight (88 pounds) and over—800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim every twelve hours.

Infants less than 2 months of age—Use is not recommended.

Infants 2 months of age and older and children up to 40 kg of weight (88 pounds)—Dose is based on body weight. The usual dose is 20 to 30 mg of sulfamethoxazole and 4 to 6 mg of trimethoprim per kg (9.1 to 13.6 mg of sulfamethoxazole and 1.8 to 2.7 mg of trimethoprim per pound) of body weight every twelve hours.

For the treatment of Pneumocystis carinii pneumonia (PCP):

Adults and children older than 2 months—Dose is based on body weight. The usual dose is 18.75 to 25 mg of sulfamethoxazole and 3.75 to 5 mg of trimethoprim per kg (8.5 to 11.4 mg of sulfamethoxazole and 1.7 to 2.3 mg of trimethoprim per pound) of body weight every six hours.

For the prevention of Pneumocystis carinii pneumonia (PCP):

Adults and teenagers—800 mg of sulfamethoxazole and 160 mg of trimethoprim once a day.

Infants and children 4 weeks of age and older—Dose is based on body size and must be determined by your doctor. There are several dosing regimens available that your doctor may choose from. One dosing regimen is 375 mg of sulfamethoxazole and 75 mg of trimethoprim per square meter of body surface two times a day, three times a week on consecutive days (e.g., Monday, Tuesday, Wednesday).

Missed Dose of Bactrim, (Trimethoprim 80mg/Sulfamethoxazole 400mg)

If you miss a dose of Bactrim, (Trimethoprim 80mg/Sulfamethoxazole 400mg) , apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage of Bactrim, (Trimethoprim 80mg/Sulfamethoxazole 400mg)

• Keep Bactrim, (Trimethoprim 80mg/Sulfamethoxazole 400mg) out of the reach of children.
• Store Bactrim, (Trimethoprim 80mg/Sulfamethoxazole 400mg) away from heat and direct light.
• Do not store Bactrim, (Trimethoprim 80mg/Sulfamethoxazole 400mg) in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause Bactrim, (Trimethoprim 80mg/Sulfamethoxazole 400mg) to break down.
• Do not keep outdated Bactrim, (Trimethoprim 80mg/Sulfamethoxazole 400mg) or Bactrim, (Trimethoprim 80mg/Sulfamethoxazole 400mg) no longer needed.
• Be sure that any discarded medicine is out of the reach of children. Keep out of the reach of children.

Precautions While Using Bactrim, (Trimethoprim 80mg/Sulfamethoxazole 400mg)

It is very important that your doctor check your progress at regular visits. Bactrim / (Sulfamethoxazole and Trimethoprim) may cause blood problems, especially if it is taken for a long time.

If your symptoms do not improve within a few days, or if they become worse, check with your doctor.

Bactrim / (Sulfamethoxazole and Trimethoprim) combinations may cause blood problems. These problems may result in a greater chance of certain infections, slow healing, and bleeding of the gums. Therefore, you should be careful when using regular toothbrushes, dental floss, and toothpicks. Dental work should be delayed until your blood counts have returned to normal. Check with your medical doctor or dentist if you have any questions about proper oral hygiene (mouth care) during treatment.

Bactrim / (Sulfamethoxazole and Trimethoprim) combinations may cause your skin to be more sensitive to sunlight than it is normally. Exposure to sunlight, even for brief periods of time, may cause a skin rash, itching, redness or other discoloration of the skin, or a severe sunburn. When you begin taking Bactrim / (Sulfamethoxazole and Trimethoprim):

Stay out of direct sunlight, especially between the hours of 10:00 a.m. and 3:00 p.m., if possible.
Wear protective clothing, including a hat and sunglasses.
Apply a sun block product that has a skin protection factor (SPF) of at least 15. Some patients may require a product with a higher SPF number, especially if they have a fair complexion. If you have any questions about this, check with your health care professional.
Apply a sun block lipstick that has an SPF of at least 15 to protect your lips.
Do not use a sunlamp or tanning bed or booth.
If you have a severe reaction from the sun, check with your doctor.

Bactrim / (Sulfamethoxazole and Trimethoprim) may also cause some people to become dizzy. Make sure you know how you react to Bactrim / (Sulfamethoxazole and Trimethoprim) before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert . If this reaction is especially bothersome, check with your doctor.

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Side Effects of Bactrim, (Trimethoprim 80mg/Sulfamethoxazole 400mg)

Along with its needed effects, Bactrim, (Trimethoprim 80mg/Sulfamethoxazole 400mg) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

More common

Itching; skin rash

Less common

Aching of joints and muscles; difficulty in swallowing; pale skin; redness, blistering, peeling, or loosening of skin; sore throat and fever; unusual bleeding or bruising ; unusual tiredness or weakness; yellow eyes or skin

Rare.

Abdominal or stomach cramps and pain (severe); abdominal or stomach tenderness; anxiety; blood in urine; bluish fingernails, lips, or skin; confusion; diarrhea (watery and severe), which may also be bloody; difficult breathing; drowsiness; fever; general feeling of illness; greatly increased or decreased frequency of urination or amount of urine; hallucinations; headache, severe; increased thirst; lower back pain; mental depression; muscle pain or weakness ; nausea; nervousness; pain at site of injection; pain or burning while urinating; seizures (convulsions); stiff neck and/or back; swelling of front part of neck.

Some of the above side effects (severe abdominal or stomach cramps and pain, and watery and severe diarrhea, which may also be bloody) may also occur up to several weeks after you stop using any of Bactrim / (Sulfamethoxazole and Trimethoprim).

Also, check with your doctor as soon as possible if the following side effect occurs:

More common

Increased sensitivity of skin to sunlight

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

More common

Diarrhea; dizziness; headache; loss of appetite; mouth sores or swelling of the tongue; nausea or vomiting; tiredness

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.

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